AGROCHEMICALS AND BIOPESTICIDES STUDIES

Quality and Accreditation

All agrochemical studies are recognized/monitored by CGCRE/INMETRO* according to Good Laboratory Practices (GLP).

NSF Bioensaios is also ISO/IEC 17025 accredited by CGCRE/INMETRO* and holds additional accreditations from Ministries of Agriculture (MAPA) and Health (ANVISA), SENASA (Argentina) and SENAVE (Paraguay).

* Brazilian Accreditation Agency

ARROBAContact us through email
 comercial.agro@nsf.org
            or by phone 55 (51) 3493.6888

 

Five Batch Analysis

Screening analysis
Evaluation of solvents and inorganics
Water content
Quantification and identification of active ingredient
Quantification and identification of impurities with concentration higher than 0.1% w/w
Quantification and identification of impurities specified as Toxicological Concern by Regulatory Agencies, such as FAO, IUPAC, INC-02* and others.
Isolation of impurities, acquisition and certification of analytical standards from the Technical Product.

*INC-02 – Joint normative instruction n° 2, issued by Ministry of Agriculture (MAPA), Ministry of Health (ANVISA) and Ministry of Environment (IBAMA) in June 20th, 2008.

Physicochemical Properties

Physical state, aspect, color and odor
Purity analysis
Molecular identification
Metallic Impurities
Boiling point/range
Melting point/range
Vapour pressure
pH
Dissociation constant in water
Complex formation constant
Partition coefficient n-octanol/water
Solubility in water and organic solvents
Miscibility in water and organic solvents
Density
Surface tension
Viscosity
Particle size distribution
Corrosivity
Accelerated and storage stability
Flash point
Volatility
Oxidizing properties
Content of active ingredient and impurities
Analytical method validation
Others

 

Pesticide Residue Study

Method development and validation of residues
Stability studies
Pesticide residue study for registration of agrochemical

Toxicological Studies

Acute oral toxicity
Acute inhalation toxicity
Acute dermal toxicity
Acute dermal Irritation/corrosion
Acute eye irritation/corrosion
Skin sensitization

Pathogenicity Studies (microbiological products)

Acute oral toxicity/pathogenicity
Acute pulmonary toxicity/pathogenicity
Acute injection toxicity/pathogenicity
Intraperitoneal toxicity/pathogenicity

Genotoxicity Studies

Bacterial reverse mutation teste – AMES test
Mammalian erythrocyte micronucleus test
In vitro micronucleus test

Environmental Behavior Studies

Photolysis (preliminary study)
Hydrolysis (preliminary study)
Ready biodegradability

Ecotoxicological Studies

Soil Microorganisms – carbon transformation test
Soil Microorganisms – nitrogen transformation test
Acute toxicity to soil organisms – earthworms
Acute oral toxicity to avian
Acute toxicity to luminescent bacteria
Algae growth inhibition test
Acute/chronic toxicity to microcrustaceans
Acute/chronic toxicity to fishes
Acute oral/contact toxicity to bees

Bee Studies

Field and semi-field (tunnel) bee trials
Honey bee (Apis mellifera) larval toxicity test, single exposure
Honey bee (Apis mellifera) larval toxicity test, repeated exposure
Honey bee toxicity of residues on foliage
Honey bee chronic toxicity 10 days

In Silico Studies

QSAR – Quantitative structure–activity relationship
Read-Across
Risk Assessment

Toxicological Alternative Methods

NSF Bioensaios is working to implement alternative methods to traditional in vivo toxicity studies.
The strategy is based on in vitro, cell cytotoxicity, cell culture and other methods.